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KMID : 1142820180020020047
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Bio, Ethics and Policy
2018 Volume.2 No. 2 p.47 ~ p.64
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Scientific Application on Genome Editing Technology and the 14-day Rule of Human Embryo
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Kim Han-Nah
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Abstract
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The Bioethics and Safety Act have adopted the “14-day rule” which refers to the basic research principle to limit human embryo research before appearing primitive streak since 2004. However, current broader scientific achievements regarding human genome editing research have re-emerged active discussion for the “14-day rule.” In particular, research on self-organization of human embryo in vitro, genome editing research regarding the animal or chimeric embryo, human organoid research and human organoid research shows evidences that justifies to extend the “14-day rule.” This article explores recent ethical and legal issues between scientific application on genome editing technology and the “14-day rule” and suggests possible considerations to discuss the revision of the “14-day rule” in the Bioethics and Safety Act for further studies.
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KEYWORD
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Bioethics and Safety Act, Human Embryo, Genome Editing, Self-organization of Human Embryo in vitro, Organoid Research
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